P33: EARLY PEANUT IMMUNOTHERAPY IN CHILDREN (EPIC) – A PRAGMATIC PEANUT ORAL IMMUNOTHERAPY PROTOCOL FOR CHILDREN UNDER 5 YEARS OF AGE

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منابع مشابه

Peanut immunotherapy

Peanut allergy is common and can be a cause of severe, life-threatening reactions. It is rarely outgrown like other food allergies, such as egg and milk. Peanut allergy has a significant effect on the quality of life of sufferers and their families, due to dietary and social restrictions, but mainly stemming from fear of accidental peanut ingestion. The current management consists of strict avo...

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Immunotherapy for peanut allergy.

Peanut allergy is one of the commonest food hypersensitivities causing fatal or near-fatal reactions. There is, currently, no preventive treatment and the incidence of severe allergic reactions during peanut desensitisation has limited its clinical use. Anti-immunoglobulin E therapy has been shown to be effective in preventing peanut-induced reactions but it does not result in long-term toleran...

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The safety of peanut oral immunotherapy in peanut-allergic subjects in a single-center trial.

BACKGROUND Peanut allergy is the leading cause of food-related anaphylaxis, and accidental exposures are common. Oral immunotherapy (OIT) has been posited as a potential treatment. METHODS Patients aged 3-65 years with peanut-specific IgE ≥7 kU/l and/or a positive skin prick test with a history of an allergic reaction to peanut were recruited to undergo an OIT protocol. All adverse reactions ...

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Peanut oral immunotherapy is not ready for clinical use.

Hippocrates wrote that ‘‘The physician must . . . have two special objects in view with regard to disease, namely, to do good or to do no harm’’ (Hippocratic Corpus, Epidemics, Bk I, Sect 5). As physicians, we are continually challenged with the task of weighing the possible risks and benefits of treatment against those of taking no action. Similarly, we pursue clinical investigation when exist...

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Peanut oral immunotherapy in adolescents: study protocol for a randomized controlled trial

BACKGROUND Peanut allergy is an increasingly common health problem. Current treatment guidelines are based on strict avoidance. However, in the last few years, oral immunotherapy protocols have shown promising results yielding increased tolerance to peanut in allergic children. Adolescence is particularly at risk. METHODS/DESIGN We have designed a randomized, double-blind, placebo-controlled,...

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ژورنال

عنوان ژورنال: Internal Medicine Journal

سال: 2022

ISSN: ['1444-0903', '1445-5994']

DOI: https://doi.org/10.1111/imj.32_15894